Article

Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity

2021-03-12

Abstract excerpt

<h4>Summary</h4> New SARS-CoV-2 variants that have accumulated multiple mutations in the spike (S) glycoprotein enable increased transmission and resistance to neutralizing antibodies. Here, we study the antigenic and structural impacts of the S protein mutations from four variants, one that was involved in transmission between minks and humans, and three that rapidly spread in human populations and originated in...

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Literature Corpus work: cfa42d1b-d0a3-5f9a-9225-abac03532c32
DOI: 10.1101/2021.03.11.435037

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