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Evolution of the SARS-CoV-2 spike protein in the human host

4 Mar 2022

Abstract excerpt

Recently emerged variants of SARS-CoV-2 contain in their surface spike glycoproteins multiple substitutions associated with increased transmission and resistance to neutralising antibodies. We have examined the structure and receptor binding properties of spike proteins from the B.1.1.7 (Alpha) and B.1.351 (Beta) variants to better understand the evolution of the virus in humans. Spikes of both variants have the...

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PMID: 35246509
DOI: 10.1038/s41467-022-28768-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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