Article
C Terminus of DJ-1 Determines Its Homodimerization, Deglycation Activity and Suppression of Ferroptosis
2020-03-26
Abstract excerpt
DJ-1 is a multi-functional protein related to cancer and autosomal early-onset Parkinson disease (PD). Besides the well-documented antioxidative stress activity, recent studies suggest that DJ-1 has the deglycation enzymatic activity and the anti-ferroptosis function. Although it has been demonstrated that DJ-1 forms the homodimerization, which dictates its antioxidative stress activity, the relationship between t...
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Identifiers and source
- Literature Corpus work
- cf284777-41f6-5e7e-b7c8-7ddadb2df6dd
- DOI
- 10.1101/2020.03.26.992446
