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<i>Saccharomyces cerevisiae</i> DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins

2022-09-23

Abstract excerpt

Reactive carbonyl species (RCS) such as methylglyoxal and glyoxal are potent glycolytic intermediates that extensively damage cellular biomolecules leading to genetic aberration and protein misfolding. Hence, RCS levels are crucial indicators in the progression of various pathological diseases. Besides the glyoxalase system, emerging studies report highly conserved DJ-1/ThiJ/PfpI superfamily proteins as critical r...

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Literature Corpus work
f9f8dd63-cc3f-5917-97bb-cd4b9fa3e5f8
DOI
10.1101/2022.09.23.509147
Open publication

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<i>Saccharomyces cerevisiae</i> DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteinsDOI 10.1101/2022.09.23.509147
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