Article
Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.
Biochemical and biophysical research communications - 13 Jan 2006
Ito Genta, Ariga Hiroyoshi, Nakagawa Yasuhito, Iwatsubo Takeshi
Abstract excerpt
A significant proportion of early onset parkinsonism is inherited as an autosomal-recessive trait (AR-EP). DJ-1 was identified as one of the causative genes for AR-EP (PARK7), and DJ-1 protein has been implicated in oxidative stress response through oxidation of one of the three cysteine residues...
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