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Article

Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease.

Neurobiology of disease - 1 Dec 2017

Biosa Alice, Sandrelli Federica, Beltramini Mariano, Greggio Elisa, Bubacco Luigi, Bisaglia Marco

Abstract excerpt

Several mutations in the gene coding for DJ-1 have been associated with early onset forms of parkinsonism. In spite of the massive effort spent by the scientific community in understanding the physiological role of DJ-1, a consensus on what DJ-1 actually does within the cells has not been reached, with several diverse functions proposed. At present, the most accepted function for DJ-1 is a neuronal protective...

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PMID: 28823929
DOI: 10.1016/j.nbd.2017.08.005

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