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Oxidative stress induces <i>E. coli</i> aryl polyene expression, sensitizing the bacterial stress response and modulating the redox environment of innate immune cells

2026-01-21

Abstract excerpt

Aryl polyenes (APEs) are specialized polyunsaturated outer membrane lipids that protect their producers from oxidative stress and contribute to biofilm formation. APEs are produced by an abundant biosynthetic gene cluster (BGC) family conserved across Gram-negative bacterial clades. The APE biosynthesis pathway involves 11 different enzymes and cumulates in the attachment of APEs to an anchor molecule in the Gram-...

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Literature Corpus work
cea1010c-f29e-5ed7-8db4-41cb040e885b
DOI
10.64898/2026.01.21.700819
Open publication

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