Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation.

NPJ biofilms and microbiomes - 2 Jul 2021

Johnston Isabel, Osborn Lucas J, Markley Rachel L, McManus Elizabeth A, Kadam Anagha, Schultz Karlee B, Nagajothi Nagashreyaa, Ahern Philip P, Brown J Mark, Claesen Jan

Abstract excerpt

Aryl polyenes (APEs) are specialized polyunsaturated carboxylic acids that were identified in silico as the product of the most widespread family of bacterial biosynthetic gene clusters (BGCs). They are present in several Gram-negative host-associated bacteria, including multidrug-resistant human pathogens. Here, we characterize a biological function of APEs, focusing on the BGC from a uropathogenic Escherichia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Biological Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biosynthetic Pathways

Share to Escherichia coli Proteins

Share to Genes, Essential

Share to Molecular Structure

Share to Oxidation-Reduction

Share to Polyenes

Source

Open in PubMed Open full text

Identifiers

PMID: 34215744
DOI: 10.1038/s41522-021-00226-3
PMCID: PMC8253772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation.PMID 34215744Read ↗

Identification of essential genes for <i>Escherichia coli</i> aryl polyene biosynthesis and function in biofilm formationSemantic proximity Read ↗

Oxidative stress induces <i>E. coli</i> aryl polyene expression, sensitizing the bacterial stress response and modulating the redox environment of innate immune cellsSemantic proximity Read ↗

Structural Comparison of Acinetobacter baumannii β-ketoacyl-acyl Carrier Protein Reductases in Fatty Acid and Aryl Polyene BiosynthesisSemantic proximity Read ↗

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters.Semantic proximity Read ↗

Caries-Associated Biosynthetic Gene Clusters in Streptococcus mutansSemantic proximity Read ↗

Biosynthetic gene cluster signature profiles of pathogenic Gram-negative bacteria isolated from Egyptian clinical settingsSemantic proximity Read ↗

Polyamine Transport Is Required for Stress Responses and Capsule Production in Streptococcus PneumoniaeSemantic proximity Read ↗

Genomic Analysis of Endophytic Bacillus-Related Strains Isolated from the Medicinal Plant Origanum vulgare L. Revealed the Presence of Metabolic Pathways Involved in the Biosynthesis of Bioactive CompoundsSemantic proximity Read ↗

Same same but different – The global response of <i>Escherichia coli</i> to five different LpxC inhibitorsSemantic proximity Read ↗

Protocatechuic acid induces endogenous oxidative stress in CR-hvKP by regulating the EMP-PPP pathwaySemantic proximity Read ↗

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficileSemantic proximity Read ↗

Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.