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Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs

21 Oct 2019

Abstract excerpt

(UPEC) is the major causative agent of uncomplicated urinary tract infections (UTIs). A common virulence genotype of UPEC strains responsible for UTIs is yet to be defined, due to the large variation of virulence factors observed in UPEC strains. We hypothesized that studying UPEC functional responses in patients might reveal universal UPEC features that enable pathogenesis. Here we identify a transcriptional...

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PMID: 31633483
DOI: 10.7554/elife.49748

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