Article

Identification of essential genes for <i>Escherichia coli</i> aryl polyene biosynthesis and function in biofilm formation

2020-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Aryl polyenes (APEs) are specialized polyunsaturated carboxylic acids that were identified in silico as the product of the most widespread family of bacterial biosynthetic gene clusters (BGCs). They are present in several Gram-negative host-associated bacteria, including multi-drug resistant human pathogens. Here, we characterize a biological function of APEs, focusing on the BGC from a uropath...

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Literature Corpus work: 531f37c7-ec76-5314-bc91-4e73d2a67652
DOI: 10.1101/2020.04.22.055939

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