Article

Structural Comparison of Acinetobacter baumannii β-ketoacyl-acyl Carrier Protein Reductases in Fatty Acid and Aryl Polyene Biosynthesis

2020-11-25

Abstract excerpt

Some gram-negative bacteria harbor lipids with aryl polyene (APE) moieties. Biosynthesis gene clusters (BGCs) for APE biosynthesis exhibit striking similarities with fatty acid synthesis (FAS) genes. Despite their broad distribution among pathogenic and symbiotic bacteria, the detailed roles of the metabolic products of APE gene clusters are unclear. Here, we determined the crystal structures of the β-ketoacyl-acy...

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Literature Corpus work: 78300c32-9401-58db-9c35-3e98d318dd2f
DOI: 10.21203/rs.3.rs-107949/v1

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