Article

Propionic acid promotes the virulent phenotype of Crohn’s disease-associated adherent-invasive <i>Escherichia coli</i>

2018-08-09

Abstract excerpt

The short chain fatty acid propionic acid (PA) is a bacteria-derived human intestinal antimicrobial and immune modulator used widely in Western food production and agriculture. Here we examine the effect of PA on the pathogenicity of the Crohn’s disease-associated microbe, adherent-invasive Escherichia coli (AIEC). Passage of AIEC through a murine model, where the low intestinal PA levels were increased to replic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 208d4e8c-6aa7-5829-9e72-b45c359397e0
DOI: 10.1101/387647

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Propionic acid promotes the virulent phenotype of Crohn’s disease-associated adherent-invasive <i>Escherichia coli</i>DOI 10.1101/387647Read

Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.Semantic proximity Read

Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn’s disease-associated <i>E. coli</i> toward enhanced pathogenicitySemantic proximity Read

Establishing the phenotypic basis of adherent-invasive <i>Escherichia coli</i> (AIEC) pathogenicity in intestinal inflammationSemantic proximity Read

Adherent-invasive Escherichia coli in Crohn’s disease: the 25th anniversarySemantic proximity Read

Evidence for a Causal Role for Escherichia coli Strains Identified as Adherent-Invasive (AIEC) in Intestinal InflammationSemantic proximity Read

<i>E. coli</i> associated with Crohn’s disease exhibit distinct strategies to colonize macrophagesSemantic proximity Read

Understanding Host-Adherent-Invasive<i>Escherichia coli</i>Interaction in Crohn’s Disease: Opening Up New Therapeutic StrategiesSemantic proximity Read

A polymicrobial view of disease potential in Crohn's-associated adherent-invasive E. coli.Semantic proximity Read

Decoding <i>E. coli</i> ’s Gut Survival Strategies: A CRISPRi Approach Across Diets, Inflammatory Environment and StrainsSemantic proximity Read

The intestinal fatty acid propionate inhibits <i><scp>S</scp>almonella</i> invasion through the post‐translational control of <scp><scp>HilD</scp></scp>Semantic proximity Read

The Role of Propionate-Induced Rearrangement of Membrane Proteins in the Formation of the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.Semantic proximity Read

A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive <i>Escherichia coli</i>Semantic proximity Read