Article

Identifying genetic regulations on immune cell type proportions and their impacts on autoimmune diseases

2026-03-01

Abstract excerpt

Genetic regulation of immune cell composition plays a crucial role in the etiology of complex diseases, yet remains poorly understood. We propose a unified analytical framework that integrates genome-wide association studies (GWAS) of cell type proportions with cell-type-wide association studies (cWAS) to systematically characterize both the genetic regulation of immune cell composition and its downstream effects...

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Literature Corpus work: ce81e2d5-27e1-549b-a737-9dba3b36ebaa
DOI: 10.64898/2026.02.26.708418

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