Article
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
2019-02-15
Abstract excerpt
Expression quantitative trait loci (eQTL) studies are used to interpret the function of disease-associated genetic risk factors. To date, most eQTL analyses have been conducted in bulk tissues, such as whole blood and tissue biopsies, which are likely to mask the cell type context of the eQTL regulatory effects. Although this context can be investigated by generating transcriptional profiles from purified cell sub...
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Identifiers and source
- Literature Corpus work
- b5070616-3dc0-552a-869b-63f8278ce423
- DOI
- 10.1101/548669