Article

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

2020-02-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Expression quantitative trait loci (eQTL) studies are used to interpret the function of disease-associated genetic risk factors. To date, most eQTL analyses have been conducted in bulk tissues, such as whole blood and tissue biopsies, which are likely to mask the cell type context of the eQTL regulatory effects. Although this context can be investigated by genera...

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Literature Corpus work: a09cf701-e3af-5bd6-823c-df92b0884d9f
DOI: 10.21203/rs.2.23416/v1

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