Article

CHD7 binds distinct regions in the <i>Sox11</i> locus to regulate neuronal differentiation

2025-04-03

Abstract excerpt

The chromodomain helicase DNA binding protein 7 (CHD7) is a nucleosome repositioner implicated in multiple cellular processes, including neuronal differentiation. We identified CHD7 genome-wide binding sites that regulate neuronal differentiation in an otic stem cell line. We identified CHD7 enrichment at the Sox11 promoter and 3’ untranslated region (UTR). Sox11 is a transcription factor essential for neuronal...

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Literature Corpus work: ce762b62-c5b1-5fa5-ad25-574af44378e8
DOI: 10.1101/2025.04.02.646816

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