Article

Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors

2022-11-04

Abstract excerpt

Neurocristopathies such as CHARGE syndrome result from aberrant neural crest development. A large proportion of CHARGE cases are attributed to mutations in the gene encoding CHD7, chromodomain helicase DNA binding protein 7, which remodels chromatin. While the role for CHD7 in neural crest development is well documented, it remains elusive how this seemingly ubiquitous factor is specifically upregulated in neural...

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Literature Corpus work: b20780ca-4b76-5c4a-94bb-aebf9294bf38
DOI: 10.1101/2022.11.03.515045

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