Article

Pharmacological Macrophage Attenuation by Imatinib Reverts Hepatic Steatosis and Inflammation in Obese Mice

2017-12-30

Abstract excerpt

<h4>Aims</h4> Non-alcoholic fatty liver disease (NAFLD) has become one of the most common liver diseases worldwide. As macrophages play a key role in NAFLD, therapies targeting macrophages have been postulated. Indeed, strategies depleting macrophages or blocking monocyte recruitment into the liver improve NAFLD, however, are not feasible in clinical practice. Our goal was to assess whether attenuation of macroph...

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Literature Corpus work: ce6bf850-8892-5a59-a0b0-92ba4fd8661e
DOI: 10.1101/241224

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