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A 1,2,3-Triazole Derivative Mitigates Palmitic Acid-Induced Lipotoxicity Through Coordinated Modulation of Lipogenic, Oxidative, and Inflammatory Pathways in HepG2 Cells

2026-07-10

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<title>Abstract</title> <p> Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterised by excessive lipid accumulation in hepatocytes, oxidative stress, mitochondrial dysfunction and inflammation, yet effective therapeutic options remain limited. Here, we investigated the protective effects of a novel 1,2,3-triazole derivative (molecule <bold>3</bold> ) in a palmitic acid (PA)-induced li...

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Literature Corpus work
65d7f301-e49c-5a4d-9b0a-cbdccf01d070
DOI
10.21203/rs.3.rs-9950723/v1
Open publication

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A 1,2,3-Triazole Derivative Mitigates Palmitic Acid-Induced Lipotoxicity Through Coordinated Modulation of Lipogenic, Oxidative, and Inflammatory Pathways in HepG2 CellsDOI 10.21203/rs.3.rs-9950723/v1
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