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Article

Compartment-specific analysis reveals disrupted astrocytic calcium transients in Alzheimer's mice

2025-06-15

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is characterized by presence of extracellular amyloid plaques, intracellular tau tangles, and extensive neuronal cell death. In addition to neurons, astrocytes modulate neuronal network activity through tripartite synapses and are increasingly recognized for their involvement in AD pathology. Astrocytic calcium signaling has been implicated in AD pathological pr...

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Literature Corpus work
ce661b4f-fc19-5e83-9f55-f85014ea3fa4
DOI
10.21203/rs.3.rs-6682029/v1
Open publication

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Compartment-specific analysis reveals disrupted astrocytic calcium transients in Alzheimer's miceDOI 10.21203/rs.3.rs-6682029/v1
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