Article

ASTRA: a deep learning algorithm for fast semantic segmentation of large-scale astrocytic networks

2023-05-03

Abstract excerpt

Changes in the intracellular calcium concentration are a fundamental fingerprint of astrocytes, the main type of glial cell. Astrocyte calcium signals can be measured with two-photon microscopy, occur in anatomically restricted subcellular regions, and are coordinated across astrocytic networks. However, current analytical tools to identify the astrocytic subcellular regions where calcium signals occur are time-co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7651417f-0ac3-53bb-8cc7-e4a2137b689b
DOI: 10.1101/2023.05.03.539211

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ASTRA: a deep learning algorithm for fast semantic segmentation of large-scale astrocytic networksDOI 10.1101/2023.05.03.539211Read

Segment2P: Parameter-free automated segmentation of cellular fluorescent signalsSemantic proximity Read

Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging.Semantic proximity Read

Compartment-specific analysis reveals disrupted astrocytic calcium transients in Alzheimer's miceSemantic proximity Read

CalmAn: An open source tool for scalable Calcium Imaging data AnalysisSemantic proximity Read

RASP: Optimal single fluorescent puncta detection in complex cellular backgroundsSemantic proximity Read

NanTex enables computational multiplexing and phenotyping of organelles across super-resolution modalitiesSemantic proximity Read

An open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neuronsSemantic proximity Read

Automated curation of CNMF-E-extracted ROI spatial footprints and calcium traces using open-source AutoML toolsSemantic proximity Read

Whole Human-Brain Mapping of Single Cortical Neurons for Profiling Morphological Diversity and StereotypySemantic proximity Read

Sparse Annotation is Sufficient for Bootstrapping Dense Neuron SegmentationSemantic proximity Read

Hemodynamic Signals Reshape Biological Inference in Widefield Calcium ImagingSemantic proximity Read

MorphoHub: A Platform for Petabyte-Scale Multi-Morphometry GenerationSemantic proximity Read