Article

Quantifying Adaptive Evolution of the Human Immune Cell Landscape

2023-10-06

Abstract excerpt

The human immune system is under constant evolutionary pressure, primarily through its role as first line of defence against pathogens. Accordingly, population genomics studies have shown that immune-related genes have a high rate of adaptive evolution. These studies, however, are mainly based on protein-coding genes without cellular context, leaving the adaptive role of cell types and states uncharted. Inferring...

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Literature Corpus work: ce468f6c-d06b-58f3-bdf9-ce7118f8a13a
DOI: 10.1101/2023.10.06.559946

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