Article
Shaping Variation in the Human Immune System.
Trends in immunology - 1 Oct 2016
Liston Adrian, Carr Edward J, Linterman Michelle A
Abstract excerpt
Immune responses demonstrate a high level of intra-species variation, compensating for the specialization capacity of pathogens. The recent advent of in-depth immune phenotyping projects in large-scale cohorts has allowed a first look into the factors that shape the inter-individual diversity of the human immune system. Genetic approaches have identified genetic diversity as drivers of 20-40% of the variation...
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