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Article

Shaping immunity: The influence of natural selection on population immune diversity.

Immunological reviews - 1 May 2024

Randolph Haley E, Aracena Katherine A, Lin Yen-Lung, Mu Zepeng, Barreiro Luis B

Abstract excerpt

Humans exhibit considerable variability in their immune responses to the same immune challenges. Such variation is widespread and affects individual and population-level susceptibility to infectious diseases and immune disorders. Although the factors influencing immune response diversity are partially understood, what mechanisms lead to the wide range of immune traits in healthy individuals remain largely...

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Identifiers

PMID: 38577999
DOI: 10.1111/imr.13329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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