Article
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse population
2019-06-02
Abstract excerpt
Many patients with Alzheimer’s dementia also exhibit non-cognitive symptoms such as sensorimotor deficits, which can precede the onset of the hallmark cognitive deficits and significantly impact daily activities and an individual’s ability to live independently. However, the mechanisms underlying sensorimotor dysfunction in AD and the relationship between sensorimotor and cognitive decline remain poorly understood...
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Identifiers and source
- Literature Corpus work
- ce42c50d-3a9c-50e0-91e7-9d323f270292
- DOI
- 10.1101/657122