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Visuo‐spatial learning and memory impairments in the 5xFAD mouse model of Alzheimer's disease: Effects of age, sex, albinism, and motor impairments

3 Mar 2022

Abstract excerpt

Abstract The 5xFAD mouse model of Alzheimer's disease (AD) rapidly develops AD‐related neuro‐behavioral pathology. Learning and memory impairments in 5xFAD mice, however, are not always replicated and the size of impairments varies considerably across studies. To examine possible sources of this variability, we analyzed the effects of age, sex, albinism due to background genes (Tyrc, Oca2p) and motor impairment...

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PMID: 35238473
DOI: 10.1111/gbb.12794

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