Article
Behavioral phenotyping of mouse models of neurodegeneration.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Dumont Magali
Abstract excerpt
Neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), Huntington's (HD), Parkinson's (PD) and Alzheimer's diseases (AD), are characterized by the loss of structure and function of specific neuronal circuitry in the brain. As a result of this loss, behavioral symptoms occur progressively. Understanding the causes of neurodegeneration is fundamental for the development of new therapeutic...
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