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A platform for efficient establishment, expansion and drug response profiling of high-grade serous ovarian cancer organoids

2022-04-21

Abstract excerpt

The broad research use of organoids from high-grade serous ovarian carcinoma (HGSC) has been hampered by low culture success rates and limited availability of fresh tumor material. Here we describe a method for generation and long-term expansion of HGSC organoids with efficacy markedly improved over previous reports (55% vs. 23-38%). We established organoids from cryopreserved material, demonstrating the feasibili...

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Literature Corpus work
ce3ac0b2-c454-5876-8cdd-0979ca5823ef
DOI
10.1101/2022.04.21.489027
Open publication

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A platform for efficient establishment, expansion and drug response profiling of high-grade serous ovarian cancer organoidsDOI 10.1101/2022.04.21.489027
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