Article
Patient‐derived organoid culture in epithelial ovarian cancers—Techniques, applications, and future perspectives
30 Sept 2023
Abstract excerpt
Epithelial ovarian cancer (EOC) is a heterogeneous disease composed of different cell types with different molecular aberrations. Traditional cell lines and mice models cannot recapitulate the human tumor biology and tumor microenvironment (TME). Patient-derived organoids (PDOs) are freshly derived from patients' tissues and are then cultured with extracellular matrix and conditioned medium. The high concordance...
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