Article

Epigenetic Control of Spatiotemporal Dynamics of Pancreatic Cancer Cells via Brg1–Rac1 Signaling

2026-05-07

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDA) arises from distinct precursor lesions with different clinical outcomes, yet the mechanisms linking epigenetic regulation to invasive cell behavior remain poorly understood. Here, we investigate how the chromatin remodeler Brg1 influences the dynamic properties of cancer cell migration. Using a biomimetic supported membrane system combined with label-free interferometric imag...

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Literature Corpus work: cdf0a7c9-457f-509f-99b1-17884afceda5
DOI: 10.64898/2026.05.04.722641

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