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Hippocampal volumes in UK Biobank are associated with APOE only in older adults

1 Oct 2024

Abstract excerpt

Abstract INTRODUCTION The hippocampus atrophies with age and is implicated in neurodegenerative disorders including Alzheimer's disease (AD). We examined the interplay between age and apolipoprotein E ( APOE ) genotype on total hippocampal volume. METHODS Using neuroimaging data from 37,463 UK Biobank participants, we applied linear regression to quantify the association of age and APOE with hippocampal volume...

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PMID: 39553251
DOI: 10.1002/dad2.70024

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