Article

Serine proteases are required to activate influenza D virus haemagglutinin-esterase fusion (HEF) protein

2026-04-16

Abstract excerpt

Influenza D virus (IDV), the most recently identified member of the Orthomyxoviridae , was first isolated from pigs but cattle have been identified as the reservoir host. To date, IDV has not been confirmed to cause human disease. Like the haemagglutinin (HA) of influenza A virus (IAV) and the haemagglutinin-esterase fusion (HEF) protein of influenza C virus (ICV), the IDV HEF is produced as a precursor protein (...

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Literature Corpus work: cd5364fb-b79a-5b1d-b29f-ea49a0258f3f
DOI: 10.64898/2026.04.16.717628

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