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Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

18 Jun 2020

Abstract excerpt

Genome-wide, polygenic risk scores (PRS) have emerged as a useful way to characterize genetic liability. There is growing evidence that PRS may prove useful for early identification of those at increased risk for certain diseases. The current potential of PRS for alcohol use disorders (AUD) remains an open question. Using data from both a population-based sample [the FinnTwin12 (FT12) study] and a high-risk...

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PMID: 32555147
DOI: 10.1038/s41398-020-00865-8

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