Article

MitoCore: A curated constraint-based model for simulating human central metabolism

2017-05-23

Abstract excerpt

<h4>Background</h4> The complexity of metabolic networks can make the origin and impact of profound changes in central metabolism occurring during disease difficult to understand. Computer simulations can help unravel this complexity, and progress has advanced in genome-scale metabolic models. However, many current models produce unrealistic results when challenged to simulate abnormal metabolism as they include...

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Literature Corpus work: cd1f5795-8a30-529c-9734-496db99c6e38
DOI: 10.1101/141101

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