Article

Identifying functional metabolic shifts in heart failure with the integration of omics data and a cardiomyocyte-specific, genome-scale model

2020-07-21

Abstract excerpt

<h4>Summary</h4> The heart is a metabolic omnivore, known to consume many different carbon substrates in order to maintain function. In diseased states, the heart’s metabolism can shift between different carbon substrates; however, there is some disagreement in the field as to the metabolic shifts seen in end-stage heart failure and whether all heart failure converges to a common metabolic phenotype. Here, we pre...

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Literature Corpus work: 2f3189ec-e727-5d75-9cb2-c725362c05ec
DOI: 10.1101/2020.07.20.212274

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