Article
Using the reconstructed genome-scale human metabolic network to study physiology and pathology.
Journal of internal medicine - 1 Feb 2012
Bordbar A, Palsson B O
Abstract excerpt
Metabolism plays a key role in many major human diseases. Generation of high-throughput omics data has ushered in a new era of systems biology. Genome-scale metabolic network reconstructions provide a platform to interpret omics data in a biochemically meaningful manner. The release of the global human metabolic network, Recon 1, in 2007 has enabled new systems biology approaches to study human physiology,...
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