Article

Cofactors revisited – predicting the impact of flavoprotein-related diseases on a genome scale

2018-06-11

Abstract excerpt

<h4>ABSTRACT</h4> Flavin adenine dinucleotide (FAD) and its precursor flavin mononucleotide (FMN) are redox cofactors that are required for the activity of more than hundred human enzymes. Mutations in the genes encoding these proteins cause severe phenotypes, including a lack of energy supply and accumulation of toxic intermediates. Ideally, patients should be diagnosed before they show symptoms so that treatmen...

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Literature Corpus work: 25fb21e7-5128-5df7-8d28-442112a6a44a
DOI: 10.1101/343624

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