Article

MitoMAMMAL: a genome scale model of mammalian mitochondria predicts cardiac and BAT metabolism

2024-07-26

Abstract excerpt

Mitochondria perform several essential functions in order to maintain cellular homeostasis and mitochondrial metabolism is inherently flexible to allow correct function in a wide range of tissues. Dysregulated mitochondrial metabolism can therefore affect different tissues in different ways which presents experimental challenges in understanding the pathology of mitochondrial diseases. System-level metabolic model...

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Literature Corpus work: fb4a0bf8-ba9f-544b-b23a-31ec86495d81
DOI: 10.1101/2024.07.26.605281

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