Article

Co-occurrence of essential gene dispensability and bypass suppressor mutations across species

2022-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Genes have been historically classified as either essential or non-essential based on their requirement for viability. However, some genes are essential in some genetic backgrounds but non-essential in others, thus challenging the binary classification of gene essentiality. Such dispensable essential genes represent a valuable model for understanding the incomplete penetrance of loss-of-function...

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Literature Corpus work: cd099973-557d-5634-86a1-eebe2cb07d7e
DOI: 10.1101/2022.11.11.516117

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