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Article

Exploring conditional gene essentiality through systems genetics approaches in yeast.

Current opinion in genetics & development - 1 Oct 2022

Bosch-Guiteras Núria, van Leeuwen Jolanda

Abstract excerpt

An essential gene encodes for a cellular function that is required for viability. Although viability is a straightforward phenotype to analyze in yeast, defining a gene as essential is not always trivial. Gene essentiality has generally been studied in specific laboratory strains and under standard growth conditions, however, essentiality can vary across species, strains, and environments. Recent systematic...

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PMID: 35939967
DOI: 10.1016/j.gde.2022.101963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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