Article
A systems-level analysis highlights microglial activation as a modifying factor in common forms of human epilepsy
2018-11-14
Abstract excerpt
The common human epilepsies are associated with distinct patterns of reduced cortical thickness, detectable on neuroimaging, with important clinical consequences. To explore underlying mechanisms, we layered MRI-based cortical structural maps from a large-scale epilepsy neuroimaging study onto highly spatially-resolved human brain gene expression data, identifying >2,500 genes overexpressed in regions of reduced c...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- ccf7ada7-2efa-5127-a539-0cbc0661950e
- DOI
- 10.1101/470518