Article

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

2022-03-22

Abstract excerpt

Mechanisms underpinning age-related variations in cortical thickness in the human brain remain poorly understood. We investigated whether inter-regional age-related variations in cortical thinning (in a multicohort neuroimaging dataset from the ENIGMA Lifespan Working Group totalling 14,248 individuals, aged 4-89 years) depended on cell-specific marker gene expression levels. We found differences amidst early-life...

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Literature Corpus work: 80a04434-2d4b-5e5a-92c8-1a9fd1104ef7
DOI: 10.1101/2022.03.21.484899

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