Back to search

Article

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

2022-05-27

Abstract excerpt

<title>Abstract</title> <p>Mechanisms underpinning neurotypical age-related variations in cortical thickness in the human brain remain insufficiently specified. Here we used cell-specific marker genes, followed by gene ontology and enrichment analyses, to quantify the association between gene-expression levels and inter-regional age-related variations in neurotypical cortical thinning using multicohort neuroimagi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3cd1899a-023b-52ae-894f-5a4a6f74d3d5
DOI
10.21203/rs.3.rs-1686228/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life StagesDOI 10.21203/rs.3.rs-1686228/v1
Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life StagesSemantic proximity
Cellular correlates of cortical thinning throughout the lifespanSemantic proximity
Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disordersSemantic proximity
Regional patterns of human cortex development correlate with underlying neurobiologySemantic proximity
Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disordersSemantic proximity
Gene transcriptional expression of cortical thinning during childhood and adolescenceSemantic proximity
Genetic associations with cortical thickness and surface area and their distinct developmental trajectoriesSemantic proximity
A Population-scale Single-cell Spatial Transcriptomic Atlas of the Human CortexSemantic proximity
Age-specific gene signatures underlying the transcriptomes and functional connectomes of human cerebral cortexSemantic proximity
MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expressionSemantic proximity
Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 yearsSemantic proximity
MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expressionSemantic proximity
Select a neighboring publication to make it the new centre.