Article

Enhancing the Fitness of Embryoid Bodies and Organoids by Chemical Cytoprotection

2022-03-23

Abstract excerpt

<h4>ABSTRACT</h4> Embryoid bodies (EBs) and self-organizing organoids derived from human pluripotent stem cells (hPSCs) recapitulate tissue development in a dish and hold great promise for disease modeling and drug development. However, current protocols are hampered by cellular stress and apoptosis during cell aggregation, resulting in variability and impaired cell differentiation. Here, we demonstrate that EBs...

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Literature Corpus work: cccbfaef-4e24-5c4e-b215-21d04e908d75
DOI: 10.1101/2022.03.21.485225

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