Article

DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pluripotent Stem Cell

2024-01-01

Abstract excerpt

<h4>ABSTRACT</h4> Human naïve pluripotent stem cells (nPSCs) can differentiate into extra-embryonic trophectoderm (TE), a critical step in the generation of the integrated embryo model termed blastoid. The current paradigm of blastoid generation necessitates the aggregation of dozens of nPSCs treated with multiple small molecule inhibitors, growth factors, or genetic modifications to initiate TE differentiation....

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Literature Corpus work: 674c236e-f96e-562d-bfa7-dbc00d7ad7ad
DOI: 10.1101/2023.12.31.573770

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