Article

Assessment of the Optimal Generation Period and Size of Human iPSC-Derived Cardiac Organoids for Cardiotoxicity Drug Testing

2023-08-14

Abstract excerpt

<title>Abstract</title> <p>Background Human-induced pluripotent stem cell-derived cardiac organoids (hiPSC-COs) have emerged as valuable tools for cardiotoxicity drug screening, given their ability to recapitulate <italic>in vivo</italic> cardiac tissue functions and facilitate rapid assessment of drug stability to prevent toxicity. However, the lack of established criteria for the differentiation period and siz...

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Literature Corpus work: 79161647-bf66-5235-b37f-8d696305f5ec
DOI: 10.21203/rs.3.rs-3204505/v1

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