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Optimizing cardiac organoid culture to enhance maturation, viability, and cardiotoxicity assessments

2025-05-04

Abstract excerpt

Development of relevant, human induced pluripotent stem cell-derived cardiac organoids is essential to recapitulate myocardium physiology and functionality for assessment of drug-induced toxicity evaluations. However, the optimal conditions for culturing self-aggregating multicellular cardiac organoids are not well-elucidated, particularly the impact of noncardiomyocytes. In this study, we generated cardiac organo...

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Identifiers and source

Literature Corpus work
9b42f380-3d25-5489-a004-359782d92b13
DOI
10.1101/2025.04.29.651308
Open publication

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Optimizing cardiac organoid culture to enhance maturation, viability, and cardiotoxicity assessmentsDOI 10.1101/2025.04.29.651308
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