Article

FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells

2022-09-28

Abstract excerpt

<h4>Summary</h4> During cortical development, human basal radial glial cells (bRGCs) are highly capable of sustained self-renewal and neurogenesis. Selective pressures on this cell type may have contributed to the evolution of the human neocortex, leading to an increase in cortical size. bRGCs have enriched expression for Forkhead Box P1 (FOXP1), a transcription factor implicated in neurodevelopmental disorders s...

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Literature Corpus work: cc8e133a-3455-5577-96c9-4b497f1f31bc
DOI: 10.1101/2022.09.28.509837

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