Article

Cell type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development

2024-06-08

Abstract excerpt

<h4>Summary</h4> FOXP1, a transcription factor enriched in the neocortex, is associated with autism spectrum disorders (ASD) and FOXP1 syndrome. Emx1 Cre/+ ;Foxp1 fl/fl conditional deletion ( Foxp1 cKO) in the mouse cortex leads to overall reduced cortex thickness, alterations in cortical lamination, and changes in the relative thickness of cortical layers. However, the developmental and cell type-specific me...

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Literature Corpus work: d337fc82-310f-5134-b7d0-f03057f4dd99
DOI: 10.1101/2024.06.08.598089

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