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Cerebellar organoids model cell type-specific <i>FOXP2</i> expression during human cerebellar development

2024-12-20

Abstract excerpt

In this study, we demonstrate the potential of cerebellar organoids for studying features of early human cerebellar development. Forkhead box protein P2 (FOXP2) is a transcription factor associated with speech and language development that is highly expressed in the developing brain. However, little attention has been directed to the study of FOXP2 in the early developing cerebellum. We used CRISPR gene editing in...

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Literature Corpus work
c8948ffd-e91a-5938-a27a-337a4e482391
DOI
10.1101/2024.12.20.628854
Open publication

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Cerebellar organoids model cell type-specific <i>FOXP2</i> expression during human cerebellar developmentDOI 10.1101/2024.12.20.628854
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